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Invisibleusg543
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 Arcade Champion: A Blast

Registered: 04/21/08
Posts: 7,259
read this if you take benzos
    #135353 - 10/21/08 11:43 PM (9 years, 29 days ago)

caffeine = no good

was actually just researching yerba mate and found:

"Caffeine is known to cause decreased blood levels of benzodiazepines such as diazepam (Valium) or alprazolam (Xanax)."

explains why 50 mg of valium did nothing to me the other night...


also i found this interesting:

Quote:

here has been some work to try to reduce the amnesic effects of benzodiazepines and a variety of different chemicals have been tried to block this effect. Some success has been noted with:

    * Ascorbic Acid (Vitamin C) : There is some preliminary evidence that high doses of Vitamin C may reduce or block benzodiazepine amnesia.
          o Parle M, Dhingra D. Ascorbic Acid : a promising memory-enhancer in mice. J PHarmacol Sci. 2003 Oct; 93(2):129-135. [PubMed Abstract]
    * Piracetam : Piracetam at high doses has been shown to reduce amnesic effects in several drugs, including benzodiazepines.
          o Pan JC, Zhang SS. [Antagonism of piracetam on the amnestic effect of diazepam in mice]. Yao Xue Xue Bao. 1996;31(2):91-4. [PubMed Abstract]
          o Lenegre A, Chermat R, Avril I, Steru L, Porsolt RD. Specificity of piracetam's anti-amnesic activity in three models of amnesia in the mouse. Pharmacol Biochem Behav. 1988 Mar;29(3):625-9. [ PubMed Abstract ]
    * Vinpocetine : Some evidence that vinpocetine may reduce amnesic effects of benzodiazepines.
          o Bhatti JZ, Hindmarch I. Vinpocetine effects on cognitive impairments produced by flunitrazepam. Int Clin Psychopharmacol. 1987 Oct;2(4):325-31. [ PubMed Abstract ]
          o Storm G, Oosterhuis B, Sollie FA, Visscher HW, Sommer W, Beitinger H, Jonkman JH. Lack of pharmacokinetic interaction between vinpocetine and oxazepam. Br J Clin Pharmacol. 1994 Aug;38(2):143-6. [ PubMed Abstract ] (note this did not show memory improvements)





plus like i've mentioned before tagament or white grapefruit juice increases the effects.

guess i'm gonna do some more experimenting  :hehehe:


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Invisiblewowitch420
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Registered: 04/22/08
Posts: 5,982
Loc: 512 TX
Re: read this if you take benzos [Re: usg543]
    #135354 - 10/21/08 11:44 PM (9 years, 29 days ago)

youre not gonna get much from valium, unless you combine with with a opiate


--------------------

        heady nugz


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InvisibleCalibrate
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Registered: 08/30/08
Posts: 381
Re: read this if you take benzos [Re: wowitch420]
    #135357 - 10/21/08 11:45 PM (9 years, 29 days ago)

ffuucccckkkk.

....white grapefruit juice you say?
:whatwhat:


--------------------
Calibrate is nothing but a mere puppet. A fictional character someone uses for entertainment purposes. Anything said by Calibrate should not be taken seriously. 100% of what Calibrate says is false.


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Invisibleusg543
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 Arcade Champion: A Blast

Registered: 04/21/08
Posts: 7,259
Re: read this if you take benzos [Re: wowitch420]
    #135358 - 10/21/08 11:47 PM (9 years, 29 days ago)

opiates do nothing for me. at all.

apparently i'm not the only one either.

Quote:

Did you also know about 30% of the population is immune to the euphoric effects of opiates? They will kill the pain, just no fun to them. It's all about how your body metabolizes things.




i have no sources to back this up at all, i asked the person who posted this to provide me with a source but i'm still waiting.


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Invisiblewowitch420
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Registered: 04/22/08
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Re: read this if you take benzos [Re: usg543]
    #135360 - 10/21/08 11:49 PM (9 years, 29 days ago)

i dont think thats true haha
i know someone that is allergic to opiates


--------------------

        heady nugz


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Invisibleusg543
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Registered: 04/21/08
Posts: 7,259
Re: read this if you take benzos [Re: Calibrate]
    #135361 - 10/21/08 11:50 PM (9 years, 29 days ago)

Quote:

Calibrate said:
ffuucccckkkk.

....white grapefruit juice you say?
:whatwhat:




100% white grapefruit juice or cimetidine (Tagamet)

you'd have to drink a ton of juice, or you could just pop a few of those pills. in my experience one glass of juice didn't really help.

Quote:

got this from Wikipedia:
"Eating grapefruits or drinking grapefruit juice while using alprazolam increases blood concentrations by inhibiting the intestinal metabolism.[38]

In fact, any drug that inhibits CYP3A4, for which alprazolam is a substrate, will increase serum concentrations of alprazolam significantly if administered prior or concurrently. Tagamet (cimetidine) is a widely used H2 blocker antacid that inhibits numerous cytochrome P450 enzymes.

Oral contraceptive pills reduce the clearance of alprazolam, which may lead to increased plasma levels of alprazolam and accumulation."




i'd do your own research, but i'd try the tagamet stuff myself. its OTC.


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InvisibleCalibrate
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Registered: 08/30/08
Posts: 381
Re: read this if you take benzos [Re: wowitch420]
    #135362 - 10/21/08 11:50 PM (9 years, 29 days ago)

being allergic to opiates would suck....


--------------------
Calibrate is nothing but a mere puppet. A fictional character someone uses for entertainment purposes. Anything said by Calibrate should not be taken seriously. 100% of what Calibrate says is false.


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Invisibleusg543
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Registered: 04/21/08
Posts: 7,259
Re: read this if you take benzos [Re: wowitch420]
    #135364 - 10/21/08 11:53 PM (9 years, 29 days ago)

Quote:

wowitch420 said:
i dont think thats true haha
i know someone that is allergic to opiates




well i get absolutely no euphoric effects to opiates/opiate like drugs. tried many different dosages many different times with hydrocodone and oxycodone. tried hydromorphone once with no luck as well. i think next thing i do is just inject some straight up heroin to see if that will do the trick.


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Invisiblewowitch420
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Re: read this if you take benzos [Re: usg543]
    #135365 - 10/21/08 11:55 PM (9 years, 29 days ago)

then dont fuck with them


--------------------

        heady nugz


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InvisibleCalibrate
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Posts: 381
Re: read this if you take benzos [Re: wowitch420]
    #135369 - 10/22/08 12:03 AM (9 years, 29 days ago)

ever try pod tea?


--------------------
Calibrate is nothing but a mere puppet. A fictional character someone uses for entertainment purposes. Anything said by Calibrate should not be taken seriously. 100% of what Calibrate says is false.


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Invisibleusg543
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Registered: 04/21/08
Posts: 7,259
Re: read this if you take benzos [Re: wowitch420]
    #135408 - 10/22/08 01:24 AM (9 years, 28 days ago)

Quote:

wowitch420 said:
then dont fuck with them




i don't :shrug:


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Invisibleusg543
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Registered: 04/21/08
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Re: read this if you take benzos [Re: Calibrate]
    #135409 - 10/22/08 01:25 AM (9 years, 28 days ago)

Quote:

Calibrate said:
ever try pod tea?




nope, maybe one day if i have extra cash and feel like experimenting.


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Invisiblestill beLIEve
State Property..Again
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Registered: 04/20/08
Posts: 17,167
Loc: a world thats not my own
Re: read this if you take benzos [Re: usg543]
    #135470 - 10/22/08 03:05 AM (9 years, 28 days ago)

i took acid and GHB today. that was fun and confusing,q


--------------------
niteowl said:
See, that term pedo gets thrown around a lot.
Is a 16 year old guy having sex w/a 16 year old girl a pedophile?
If not, then how is a 30 year old considered a pedophile for doing the same thing?
I think y'all need to look up the definition for pedophile.


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OfflineCoaster
I'm Back Baby
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Registered: 04/23/08
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Re: read this if you take benzos [Re: still beLIEve]
    #135471 - 10/22/08 03:06 AM (9 years, 28 days ago)

lol i thought the title read
read this until u take benzos
so i went and bought some
then started readin
:dazedandconfused:


--------------------


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OfflinePicklez
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Registered: 04/20/08
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Re: read this if you take benzos [Re: Coaster]
    #135484 - 10/22/08 04:32 AM (9 years, 28 days ago)

Vitamin C is helpful for potentating any drug


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OfflinePicklez
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Re: read this if you take benzos [Re: Picklez]
    #135485 - 10/22/08 04:40 AM (9 years, 28 days ago)

and benzos are sick. I spent my entire day barred out. Made school much more enjoyable


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Invisiblebeatyou
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Re: read this if you take benzos [Re: Picklez]
    #135581 - 10/22/08 12:54 PM (9 years, 28 days ago)

i can only enjoy xanax in the .5 to 1mg range, anything more and i just lay down or sit in an awake coma.


--------------------
this is me on a bar, 3 methrolls (up 4 days), ketamine, and some good acid two years ago.


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OfflineKing Koopa
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Re: read this if you take benzos [Re: Coaster]
    #694596 - 11/19/13 11:19 PM (3 years, 11 months ago)

Quote:

Coaster said:
lol i thought the title read
read this until u take benzos
so i went and bought some
then started readin
:dazedandconfused:





:smile:


--------------------
Alcoholics Anonymous is a fellowship of men and women who share their experience, strength and hope with each other that they may solve their common problem and help others to recover from alcoholism.

The only requirement for membership is a desire to stop drinking. There are no dues or fees for A.A. membership; we are self-supporting through our own contributions. A.A. is not allied with any sect, denomination, politics, organization or institution; does not wish to engage in any controversy; neither endorses nor opposes any causes. Our primary purpose is to stay sober and help other alcoholics to achieve sobriety.


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InvisibleHawksresurrection
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Registered: 12/05/08
Posts: 13,427
Re: read this if you take benzos [Re: King Koopa]
    #694621 - 11/20/13 03:22 AM (3 years, 11 months ago)

I just took some benzos, no caffeine, but there is some booze invloved


--------------------
Dude she isn't as young as she use to be.

-niteowl


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InvisibleUltimateDevotion
TwistedByDesign
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Re: read this if you take benzos [Re: Hawksresurrection]
    #694625 - 11/20/13 10:08 AM (3 years, 11 months ago)

What the holy fuck?


--------------------
Harry Detroit in 304 made one last promise now
"I'm goin out without a trace, a vanishing act before your eyes"


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