Home | Community | Message Board


World Seed Supply
Please support our sponsors.


Welcome to the Growery Message Board! You are experiencing a small sample of what the site has to offer. Please login or register to post messages and view our exclusive members-only content. You'll gain access to additional forums, file attachments, board customizations, encrypted private messages, and much more!

Shop: Bridgetown Botanicals Bridgetown Botanicals, CBD Capsules   Kraken Kratom Kratom Capsules for Sale   Original Sensible Seeds High THC Strains

Jump to first unread post Pages: 1
InvisibleHarry_Ba11sachM
cannoisseur
 User Gallery

Registered: 04/20/08
Posts: 11,753
Loc: Nepal Flag
A molecular link between the active component of marijuana and Alzheimer's disease pathology.
    #493089 - 10/29/10 08:20 AM (13 years, 4 months ago)

www.ncbi.nlm.nih.gov/pubmed/17140265

A molecular link between the active component of marijuana and Alzheimer's disease pathology.
Eubanks LM, Rogers CJ, Beuscher AE 4th, Koob GF, Olson AJ, Dickerson TJ, Janda KD.

Department of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
Abstract
Alzheimer's disease is the leading cause of dementia among the elderly, and with the ever-increasing size of this population, cases of Alzheimer's disease are expected to triple over the next 50 years. Consequently, the development of treatments that slow or halt the disease progression have become imperative to both improve the quality of life for patients and reduce the health care costs attributable to Alzheimer's disease. Here, we demonstrate that the active component of marijuana, Delta9-tetrahydrocannabinol (THC), competitively inhibits the enzyme acetylcholinesterase (AChE) as well as prevents AChE-induced amyloid beta-peptide (Abeta) aggregation, the key pathological marker of Alzheimer's disease. Computational modeling of the THC-AChE interaction revealed that THC binds in the peripheral anionic site of AChE, the critical region involved in amyloidgenesis. Compared to currently approved drugs prescribed for the treatment of Alzheimer's disease, THC is a considerably superior inhibitor of Abeta aggregation, and this study provides a previously unrecognized molecular mechanism through which cannabinoid molecules may directly impact the progression of this debilitating disease.


--------------------

Extras: Filter Print Post Top
OfflineDieselB
High Watt Closet
Male

Registered: 02/10/10
Posts: 1,156
Last seen: 9 years, 27 days
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: Harry_Ba11sach]
    #493092 - 10/29/10 08:24 AM (13 years, 4 months ago)

Thats pretty awesome, cannabinoids win again. Alzheimers is some scary shit too. Another thing somebody told me: in 50 years 1 in 3 will be diabetic. I don't even wanna know if it's true.

Edited by Dr. Siekadellyk (10/29/10 09:04 AM)

Extras: Filter Print Post Top
InvisibleDr. SiekadellykM
Question Everything!
Male User Gallery


Folding@home Statistics
Registered: 04/20/09
Posts: 9,365
Loc: Ketamine Flag
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: DieselB]
    #493093 - 10/29/10 08:27 AM (13 years, 4 months ago)

Quote:

Thats pretty awesome, cannabinoids win again.



:thumbup::yesnod:

This right here should be a good enough reason alone to medically legalize it throughout the country.
but no they are not that smarts.


--------------------
The Kratom Report...

Extras: Filter Print Post Top
OfflineDieselB
High Watt Closet
Male

Registered: 02/10/10
Posts: 1,156
Last seen: 9 years, 27 days
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: Dr. Siekadellyk]
    #493105 - 10/29/10 09:01 AM (13 years, 4 months ago)

You could've quoted after my non-typin ass edited.


--------------------
If you ain't smokin' dro, you're smokin' reggie. :shrug:

Extras: Filter Print Post Top
InvisibleDr. SiekadellykM
Question Everything!
Male User Gallery


Folding@home Statistics
Registered: 04/20/09
Posts: 9,365
Loc: Ketamine Flag
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: DieselB]
    #493106 - 10/29/10 09:04 AM (13 years, 4 months ago)

haha I didnt even notice until you mentioned it, but you also still spelled it wrong after the edit.:lol:

I'll fix it for you.


--------------------
The Kratom Report...

Extras: Filter Print Post Top
OfflineDieselB
High Watt Closet
Male

Registered: 02/10/10
Posts: 1,156
Last seen: 9 years, 27 days
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: Dr. Siekadellyk]
    #493107 - 10/29/10 09:06 AM (13 years, 4 months ago)

I know, and I edited twice! :sohighman: Wake and bake kicked my ass today.


--------------------
If you ain't smokin' dro, you're smokin' reggie. :shrug:

Extras: Filter Print Post Top
Jump to top Pages: 1

Shop: Bridgetown Botanicals Bridgetown Botanicals, CBD Capsules   Kraken Kratom Kratom Capsules for Sale   Original Sensible Seeds High THC Strains


Similar ThreadsPosterViewsRepliesLast post
* Researchers Suspect Link Between Synthetic Marijuana and Stroke Deadkndys420 1,098 5 11/24/13 11:22 AM
by niteowl
* How active is the Growery? Marijuana 2,029 8 01/11/09 06:15 PM
by TripityDooDaDay
* Growery: Lets have an honest talk about Marijuana
( 1 2 3 4 all )
Weed 43,145 61 12/26/12 10:22 AM
by sloantbone
* good information about known marijuana myths
( 1 2 all )
brandongoeshiyaa 14,061 32 11/06/09 02:54 PM
by DANK
* Marijuana may help delay Alzheimer’s symptoms godspeedyou 2,252 5 05/06/09 11:36 AM
by Hydro
* Cannabis and Alzheimer's disease FRACTALife 1,341 6 07/20/11 07:02 PM
by FRACTALife
* Marijuana might cause new cell growth in the brain BigBudz 2,252 2 01/19/11 10:31 AM
by sunxshine
* The World's Top Marijuana Travel Destinations According to CNBC
( 1 2 all )
FurrowedBrowM 14,220 26 06/15/10 05:08 PM
by SmOakland

Extra information
You cannot start new topics / You cannot reply to topics
HTML is disabled / BBCode is enabled
Moderator: FurrowedBrow, Harry_Ba11sach, Magash, Data, Stoneth, Dr. Siekadellyk
1,538 topic views. 3 members, 350 guests and 415 web crawlers are browsing this forum.
[ Show Images Only | Sort by Score | Print Topic ]
Search this thread:
Cannabis Seeds UK
Please support our sponsors.

Copyright 1997-2024 Mind Media. Some rights reserved.

Generated in 0.027 seconds spending 0.008 seconds on 14 queries.