Home | Community | Message Board


World Seed Supply
Please support our sponsors.

Community >> The Smoke Lounge

Welcome to the Growery Message Board! You are experiencing a small sample of what the site has to offer. Please login or register to post messages and view our exclusive members-only content. You'll gain access to additional forums, file attachments, board customizations, encrypted private messages, and much more!

Jump to first unread post. Pages: 1
InvisibleHarry_Ba11sachM
cannoisseur
 User Gallery

Registered: 04/20/08
Posts: 11,753
Loc: Nepal Flag
A molecular link between the active component of marijuana and Alzheimer's disease pathology.
    #493089 - 10/29/10 10:20 AM (6 years, 1 month ago)

www.ncbi.nlm.nih.gov/pubmed/17140265

A molecular link between the active component of marijuana and Alzheimer's disease pathology.
Eubanks LM, Rogers CJ, Beuscher AE 4th, Koob GF, Olson AJ, Dickerson TJ, Janda KD.

Department of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
Abstract
Alzheimer's disease is the leading cause of dementia among the elderly, and with the ever-increasing size of this population, cases of Alzheimer's disease are expected to triple over the next 50 years. Consequently, the development of treatments that slow or halt the disease progression have become imperative to both improve the quality of life for patients and reduce the health care costs attributable to Alzheimer's disease. Here, we demonstrate that the active component of marijuana, Delta9-tetrahydrocannabinol (THC), competitively inhibits the enzyme acetylcholinesterase (AChE) as well as prevents AChE-induced amyloid beta-peptide (Abeta) aggregation, the key pathological marker of Alzheimer's disease. Computational modeling of the THC-AChE interaction revealed that THC binds in the peripheral anionic site of AChE, the critical region involved in amyloidgenesis. Compared to currently approved drugs prescribed for the treatment of Alzheimer's disease, THC is a considerably superior inhibitor of Abeta aggregation, and this study provides a previously unrecognized molecular mechanism through which cannabinoid molecules may directly impact the progression of this debilitating disease.


--------------------


Post Extras: Print Post  Remind Me! Notify Moderator
OfflineDieselB
High Watt Closet
Male

Registered: 02/10/10
Posts: 1,156
Last seen: 1 year, 9 months
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: Harry_Ba11sach]
    #493092 - 10/29/10 10:24 AM (6 years, 1 month ago)

Thats pretty awesome, cannabinoids win again. Alzheimers is some scary shit too. Another thing somebody told me: in 50 years 1 in 3 will be diabetic. I don't even wanna know if it's true.


Edited by Dr. Siekadellyk (10/29/10 11:04 AM)


Post Extras: Print Post  Remind Me! Notify Moderator
InvisibleDr. SiekadellykM
Question Everything!
Male User Gallery Arcade Champion: Plumber, Radial Snake


Folding@home Statistics
Registered: 04/20/09
Posts: 9,305
Loc: Ketamine Flag
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: DieselB]
    #493093 - 10/29/10 10:27 AM (6 years, 1 month ago)

Quote:

Thats pretty awesome, cannabinoids win again.



:thumbup::yesnod:

This right here should be a good enough reason alone to medically legalize it throughout the country.
but no they are not that smarts.


--------------------
The Kratom Report...


Post Extras: Print Post  Remind Me! Notify Moderator
OfflineDieselB
High Watt Closet
Male

Registered: 02/10/10
Posts: 1,156
Last seen: 1 year, 9 months
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: Dr. Siekadellyk]
    #493105 - 10/29/10 11:01 AM (6 years, 1 month ago)

You could've quoted after my non-typin ass edited.


--------------------
If you ain't smokin' dro, you're smokin' reggie. :shrug:


Post Extras: Print Post  Remind Me! Notify Moderator
InvisibleDr. SiekadellykM
Question Everything!
Male User Gallery Arcade Champion: Plumber, Radial Snake


Folding@home Statistics
Registered: 04/20/09
Posts: 9,305
Loc: Ketamine Flag
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: DieselB]
    #493106 - 10/29/10 11:04 AM (6 years, 1 month ago)

haha I didnt even notice until you mentioned it, but you also still spelled it wrong after the edit.:lol:

I'll fix it for you.


--------------------
The Kratom Report...


Post Extras: Print Post  Remind Me! Notify Moderator
OfflineDieselB
High Watt Closet
Male

Registered: 02/10/10
Posts: 1,156
Last seen: 1 year, 9 months
Re: A molecular link between the active component of marijuana and Alzheimer's disease pathology. [Re: Dr. Siekadellyk]
    #493107 - 10/29/10 11:06 AM (6 years, 1 month ago)

I know, and I edited twice! :sohighman: Wake and bake kicked my ass today.


--------------------
If you ain't smokin' dro, you're smokin' reggie. :shrug:


Post Extras: Print Post  Remind Me! Notify Moderator
Jump to top. Pages: 1

Community >> The Smoke Lounge

Similar ThreadsPosterViewsRepliesLast post
* Growery: Lets have an honest talk about Marijuana
( 1 2 3 4 all )
Weed 26,330 61 12/26/12 12:22 PM
by sloantbone
* good information about known marijuana myths
( 1 2 all )
brandongoeshiyaa 6,347 32 11/06/09 04:54 PM
by DANK
* Marijuana may help delay Alzheimer’s symptoms godspeedyou 1,194 5 05/06/09 01:36 PM
by Hydro
* The World's Top Marijuana Travel Destinations According to CNBC
( 1 2 all )
FurrowedBrowM 6,409 26 06/15/10 07:08 PM
by SmOakland
* A budget cure: Marijuana taxes? spacemonkey69 1,079 2 05/09/09 05:07 PM
by godspeedyou
* Check out this morons anti "Marijuana" wesite.
( 1 2 all )
LordOfChaos 4,903 25 06/22/11 01:38 PM
by onlyone1147
* Famous Marijuana "Quotes" Linux 2,763 15 09/26/08 06:29 PM
by mel_lonta_tauda
* Long term effects of smoking marijuana.
( 1 2 3 all )
Homosapian 3,939 44 03/11/10 02:25 PM
by FurrowedBrow

Extra information
You cannot start new topics / You cannot reply to topics
HTML is disabled / BBCode is enabled
Moderator: FurrowedBrow, Harry_Ba11sach, Stoneth, Dr. Siekadellyk
740 topic views. 4 members, 150 guests and 46 web crawlers are browsing this forum.
[ Toggle Favorite | Print Topic | Stats ]
Search this thread:
Vaposhop
Please support our sponsors.

Copyright 1997-2016 Mind Media. Some rights reserved.

Generated in 0.033 seconds spending 0.004 seconds on 14 queries.