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 poke smot!
Is it 420 yet?
Registered: 04/20/08
Posts: 60
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 JWH carciniogenicity 
#393335 - 03/31/10 04:45 PM (16 years, 4 months ago) |
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Just popping in so my account remains not-inactive 
To those of you who smoke jwh-018:
Quote:
The molecule has an unsubstituted naphtalene ring attached. Taking in account the metabolic pathways suggested on the following paragraph, it is quite possible that it produces epoxides as metabolism intermediates. Epoxides are known to be carcinogenic.
Does this make you weary of the synthpot? I guess the spice people didn't think about this before putting everyone elses' health at risk.
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 THEBats
The Bridge Master
Registered: 04/20/08
Posts: 8,488
Last seen: 13 years, 1 month
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Re: JWH carciniogenicity [Re: poke smot!]
#393341 - 03/31/10 04:52 PM (16 years, 4 months ago) |
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Source? I hope not bluelight...
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kickin-two-hundo said:
you know what i did in english class? I came to class stoned out of my mind every day, i chugged vodka in the back of class, i put dead fish in the ceiling tiles. i put a gallon of old milk and orange juice in the file cabinet before winter vacation. i brought snakes in a tied up sweater and let them loose during class. i didnt go to school to learn, i went because i had to. i didnt care, and i didn't fucking listen to that stupid bitch. and i still don't fucking care. i tore the pages out of her books and burned them, and threw away all the books in the class, two books per day. 
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poke smot!
Is it 420 yet?
Registered: 04/20/08
Posts: 60
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Re: JWH carciniogenicity [Re: THEBats]
#393367 - 03/31/10 05:44 PM (16 years, 4 months ago) |
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Wikipedia.
Quote:
Metabolism: For JWH-018, the N-dealkyl metabolite could be detected as well as the hydroxylated metabolite. The highest signals could be observed for the hydroxylated N-dealkyl metabolites. Hydroxylation took place in the side chain and in both aromatic systems, the naphthalene and the indol part, which could be shown by mass shift of the corresponding fragments and by MS3 experiments.
From, "Studies on the metabolism of JWH-018 and of a homologue of CP 47,497, pharmacologically active ingredients of different misused incense (“Spice”) using GC-MS and LC-MSn techniques - T. Kraemer, K.Y. Rust, M.R. Meyer, D.K. Wissenbach, D. Bregel, M. Hopf, H.H. Maurer, J. Wilske (Institute of Legal Medicine, Saarland University, 66421 Homburg, Germany"
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RasJeph
Psycho Pete
Registered: 01/14/09
Posts: 11,657
Loc: Bumfuckt Egypt
Last seen: 2 years, 8 months
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Re: JWH carciniogenicity [Re: THEBats]
#393386 - 03/31/10 06:14 PM (16 years, 4 months ago) |
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THEBats said:
Source? I hope not bluelight...
Certainly my first though too.
Also - I don't care, because I eat it most of the time anyway.
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Of course it's happening inside your head.
Why should that mean it isn't real?
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DungenessDank
Lord of the Flies
Registered: 05/05/08
Posts: 9,372
Loc: PNW
Last seen: 13 years, 2 months
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Re: JWH carciniogenicity [Re: RasJeph]
#393388 - 03/31/10 06:17 PM (16 years, 4 months ago) |
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I would think that it would be carcinogenic no matter how you ingested it.
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FurrowedBrow
Free yourself from yourself
Registered: 04/20/08
Posts: 12,045
Loc: Carpal Tunnel
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Re: JWH carciniogenicity [Re: RasJeph]
#393391 - 03/31/10 06:37 PM (16 years, 4 months ago) |
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RasJeph said:
THEBats said:
Source? I hope not bluelight...
Certainly my first though too.
Also - I don't care, because I eat it most of the time anyway.
you eat jwh? 
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poke smot!
Is it 420 yet?
Registered: 04/20/08
Posts: 60
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Re: JWH carciniogenicity [Re: FurrowedBrow]
#393414 - 03/31/10 07:23 PM (16 years, 4 months ago) |
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I've read that it's bio-availability orally is pretty crappy.
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RasJeph
Psycho Pete
Registered: 01/14/09
Posts: 11,657
Loc: Bumfuckt Egypt
Last seen: 2 years, 8 months
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Re: JWH carciniogenicity [Re: FurrowedBrow]
#393447 - 03/31/10 08:33 PM (16 years, 4 months ago) |
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Quote:
FurrowedBrow said:you eat jwh?
Sure do. It works real well for me 
Also - yeah, I see how it could be carcinogenic either way with this one. I was thinking this was a copy-pasta of another I had read that said something about it only really being bad when smoked.
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Of course it's happening inside your head.
Why should that mean it isn't real?
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NobodyImportant
Science Is Subculture
Registered: 05/03/08
Posts: 4,981
Loc: Jawjuh.
Last seen: 13 years, 3 months
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Re: JWH carciniogenicity [Re: RasJeph]
#393585 - 04/01/10 12:13 AM (16 years, 4 months ago) |
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yeah im trying to stop smoking JWH completely, its only really a problem when im broke since I have like three grams arms reach from my bed and I just have do pour a tiny bit on some foil to get nice and blazed
Im still working on getting the oral dosages right, i hear soaking it in an oil helps it absorb better
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Glass By: US Tubes, ZOB, Roor.de, Sheldon Black, Jerome Baker, Medicali, Kennaroo, Sand, Alex K, Local and Unknown Artists
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RasJeph
Psycho Pete
Registered: 01/14/09
Posts: 11,657
Loc: Bumfuckt Egypt
Last seen: 2 years, 8 months
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I'm still trying to get a fucking mg scale (even a cheap ebay one) so I can make my chocolates right.
Once I get that down, I'm going to buy like 10 grams, make it into chocolates and just be set for life
My chocolates have all worked...granted, some better than others (some too good!)...once I know the formula, I'm happy to post the recipe up here.
Right now, I just use 10 chocolate chips (well, butterscotch, because its all we have) and eyeball the powder in. I put the chips in a metal measuring cup, set it over a slot in the toaster, and "toast". It heats the shit up, I dump the eyeballed powder in, mix, put it in the freezer and its good to go in like 10 minutes. Once I have it perfected, I have neat ice cube trays with shapes...but I'm waiting on that.
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Of course it's happening inside your head.
Why should that mean it isn't real?
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