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OfflineRasJeph
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serotonin
    #572794 - 07/17/11 04:10 PM (12 years, 9 months ago)

last friday i did methylone my first time and loved it. the next day it made me feel like shit and depressed. i assume its bc of my serotonin levels being outta whack.

its been a week and 2 days, my buddy and his sisters wanna do some with me tomorrow. should i be recovered enough? i dont wanna feel shitty while everyone else is partying down. oh, and dying. i dont wanna do  that either.


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Of course it's happening inside your head.
Why should that mean it isn't real?

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OfflinePicklez
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Re: serotonin [Re: RasJeph]
    #572796 - 07/17/11 04:19 PM (12 years, 9 months ago)

5-htp helps with serotonin recovery

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OfflineSlave of Cthulhu
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Re: serotonin [Re: Picklez]
    #572800 - 07/17/11 04:34 PM (12 years, 9 months ago)

I was gonna say the same thing. After you roll, take one of these bad boys right before you go to sleep. Shit helps out soooooooo much. I always feel fine the next day.



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OfflineRasJeph
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Re: serotonin [Re: Picklez]
    #572801 - 07/17/11 04:35 PM (12 years, 9 months ago)

good call, ill  look into it.

but this is like an "oh shit i gotta know now" deal :P ill try it after this time if im good to go.


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Of course it's happening inside your head.
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OfflineSlave of Cthulhu
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Re: serotonin [Re: RasJeph]
    #572803 - 07/17/11 04:45 PM (12 years, 9 months ago)

5-HTP is artificial Serotonin, it's guaranteed to help you after a roll bro. I promise it will get you feelin right again. I advise takin 100mg though.


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Offlinemellowparty
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Re: serotonin [Re: Slave of Cthulhu]
    #572804 - 07/17/11 04:50 PM (12 years, 9 months ago)

Its not artificial serotonin but it only differs from serotonin by one carboxyl group which is easily removed by some decarboxylase thangs in the liver(?) I think.

I think I read somewhere that it could be hepatotoxic but I wouldn't worry too much about it.


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Offlinem3kgt
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Re: serotonin [Re: mellowparty]
    #572808 - 07/17/11 05:16 PM (12 years, 9 months ago)

I'll be pickin some of that 5-HTP later today. I rolled on 400mg's of good molly last night. I feel alright though. I took some valerian root and melatoin last night with some gatorade, so I slept off the come down.


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Invisiblenannybooboo
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Re: serotonin [Re: m3kgt]
    #572809 - 07/17/11 05:18 PM (12 years, 9 months ago)

if someone has a decent batch of molly, why don't they just combine some 5-htp with it in a capsule?

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OfflineRasJeph
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Re: serotonin [Re: nannybooboo]
    #572812 - 07/17/11 05:30 PM (12 years, 9 months ago)

My guess is that you wouldn't want it DURING, but for after?

Also, Dollar General...no has :sad:

Although I did buy some green tea capsuels so I can cap up the rest of my m1 lol.


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Of course it's happening inside your head.
Why should that mean it isn't real?

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OfflineSlave of Cthulhu
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Re: serotonin [Re: nannybooboo]
    #572818 - 07/17/11 05:46 PM (12 years, 9 months ago)

Combining it with Ecstasy or Molly wouldn't do anythin special. It's not a booster in any way but more for recovery. Never take it before or during a roll. That's just stupid. Always take it after.


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OfflineSlave of Cthulhu
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Re: serotonin [Re: RasJeph]
    #572819 - 07/17/11 05:48 PM (12 years, 9 months ago)

You can find it at stores like Fred Meyers, WalMart, SafeWay etc.


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InvisibleFurrowedBrowM
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Re: serotonin [Re: m3kgt]
    #572820 - 07/17/11 05:51 PM (12 years, 9 months ago)

Quote:

Slave of Cthulhu said:
I was gonna say the same thing. After you roll, take one of these bad boys right before you go to sleep. Shit helps out soooooooo much. I always feel fine the next day.






I could have used that advice a week ago.  :lol:  took 400 mg of mdma last saturday.  the following day was one of the worst of my life.  never been in the pit of despair like that.  they also have 5htp at walgreens i learned.

Quote:

m3kgt said:
I'll be pickin some of that 5-HTP later today. I rolled on 400mg's of good molly last night. I feel alright though. I took some valerian root and melatoin last night with some gatorade, so I slept off the come down.




:lol:  nice planning!


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Multidisciplinary Association for Psychedelic Studies - Become a member!
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OfflineFRACTALife
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Re: serotonin [Re: FurrowedBrow]
    #572823 - 07/17/11 06:01 PM (12 years, 9 months ago)

That 5-HTP is not artificial serotonin, it's very similar to serotonin, but could possibly help regulate your serotonin and increase levels.


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Invisibledrawde
Registered: 11/15/09
Posts: 5,268
Re: serotonin [Re: RasJeph]
    #572824 - 07/17/11 06:02 PM (12 years, 9 months ago)

Its worth mentioning that artificial sweeteners will fuck with your serotonin, not to mention an array of other negative affects. Best to avoid all together but in an extra taxing situation especially.


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King Koopa said:
The amount of pot that Gask smokes is equivalent to a guy shooting heroin on weekends

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OfflineRasJeph
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Re: serotonin [Re: drawde]
    #572826 - 07/17/11 06:07 PM (12 years, 9 months ago)

Thanks for the heads ups. Unfortunately anything better than Dollar General is a 30+ minute drive for me :lol:

Next time I'm at Walmart I'll do it up. I gotta buy a tent soon.


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Of course it's happening inside your head.
Why should that mean it isn't real?

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OfflineSubHuman
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Registered: 07/16/11
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Re: serotonin [Re: RasJeph]
    #572832 - 07/17/11 06:36 PM (12 years, 9 months ago)

Dollar general never has any of the OTC meds I want.  I always look there first because once I found Tagament HB at a dollar store and now everytime I want to buy it I have to pay 8$ dollars at walmart or anywhere else.  Its only 8$ but it pisses me off having to pay that for a fucking antacid.

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Offlinexbcnfujv
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Re: serotonin [Re: SubHuman]
    #572835 - 07/17/11 06:46 PM (12 years, 9 months ago)

you're better off eating a full-serving of fruits and vegetables.

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OfflineSlave of Cthulhu
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Re: serotonin [Re: xbcnfujv]
    #572838 - 07/17/11 07:01 PM (12 years, 9 months ago)

All I have to say is, I've rolled close to 40 times now. I lost count after 30, haha. But EVERY time after I rolled I took a 100mg 5-HTP right before I went to sleep and felt just fine the next day. There was ONE time that I rolled hard and didn't take 5-HTP and it was fuckin rough... I don't care what anyone says, that stuff is great and I advise it to anyone who indulges in MDMA based drugs. My Serotonin levels seem quite fine to me and I have had no adverse effects from takin 5-HTP so just nut up and do it otherwise your brain is gonna fuckin hate you. Of course fruit and veggies help too but they won't replenish all the Serotonin your brain pumped out durin the roll like 5-HTP will.


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OfflineRasJeph
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Re: serotonin [Re: Slave of Cthulhu]
    #572841 - 07/17/11 07:16 PM (12 years, 9 months ago)

And for $6 per 100 pills, even a placebo effect is good. (I know its not, just sayin'.)

I'll def. be picking some up asap.


--------------------
Of course it's happening inside your head.
Why should that mean it isn't real?

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OfflineSlave of Cthulhu
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Re: serotonin [Re: RasJeph]
    #572843 - 07/17/11 07:21 PM (12 years, 9 months ago)

Glad to hear it, it's def no placebo that's for sure. I just want people to take care of themselves as much as possible. Especially when it comes to drugs that have the ability to take your life if done recklessly.


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Offlineninja cat 09
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Re: serotonin [Re: Slave of Cthulhu]
    #572877 - 07/17/11 08:37 PM (12 years, 9 months ago)

I recall reading that consuming cannabis during the roll also helped greatly with the crash, might be speaking out of my ass though.


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OfflineSlave of Cthulhu
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Re: serotonin [Re: ninja cat 09]
    #572878 - 07/17/11 08:38 PM (12 years, 9 months ago)

Nah, it really does. I love smokin on the come-down. It helps ease your mind and body so much. Never smoke before you peak though, it tends to kill it...


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Invisiblestill beLIEve
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Registered: 04/20/08
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Re: serotonin [Re: Slave of Cthulhu]
    #572907 - 07/17/11 11:01 PM (12 years, 8 months ago)

you actually want to take the 5 htp before im pretty sure

and thats weird with you and methylone. my friends take it every weekend and they love it because there is next to no hangover like with mdma. they roll hard for the weekend, some taking gram+ doses and are always fine the next day.

well, relatively fine considering the amount they eat. no where near where mdma would make them feel though.


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niteowl said:
See, that term pedo gets thrown around a lot.
Is a 16 year old guy having sex w/a 16 year old girl a pedophile?
If not, then how is a 30 year old considered a pedophile for doing the same thing?
I think y'all need to look up the definition for pedophile.

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OfflineSubHuman
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Re: serotonin [Re: still beLIEve]
    #572910 - 07/18/11 12:13 AM (12 years, 8 months ago)

I want to get some methylone but Im worried it'd show on a UA.  The shit is so cheap and easy to get too I dont wanna miss out on it if its as euphoric as its claimed to be.

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Invisiblestill beLIEve
State Property..Again
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Registered: 04/20/08
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Re: serotonin [Re: SubHuman]
    #572915 - 07/18/11 12:28 AM (12 years, 8 months ago)

oh its good shit

and i dont *think* it will show on a UA. i know MDPV wont at least.

that being said im not gonna be the test rat for it.


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niteowl said:
See, that term pedo gets thrown around a lot.
Is a 16 year old guy having sex w/a 16 year old girl a pedophile?
If not, then how is a 30 year old considered a pedophile for doing the same thing?
I think y'all need to look up the definition for pedophile.

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OfflineSlave of Cthulhu
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Re: serotonin [Re: still beLIEve]
    #572931 - 07/18/11 06:27 AM (12 years, 8 months ago)

Nah, After bro.


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OfflineRasJeph
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Re: serotonin [Re: still beLIEve]
    #572937 - 07/18/11 08:18 AM (12 years, 8 months ago)

Quote:

still beLIEve said:and thats weird with you and methylone. my friends take it every weekend and they love it because there is next to no hangover like with mdma. they roll hard for the weekend, some taking gram+ doses and are always fine the next day.





My problem wasn't that it fucked me up the next day, it was that I dosed again too soon I think.

Will letcha know how it goes today in this thread later.

Going to the casino because I got a "$10 free play" ticket and $10 meal credit for free. I've never spent a dime in that shit hole and they keep sending me free money. Fuck yeah.


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Of course it's happening inside your head.
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OfflineRasJeph
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Re: serotonin [Re: RasJeph]
    #572990 - 07/18/11 02:07 PM (12 years, 8 months ago)

lol well we both really enjoy it. he had a second where he got the fear, but i helped him out. im back to base but hes about half the size of me and he seems to still be going.

sweet :]


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Of course it's happening inside your head.
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OfflineSaki
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Re: serotonin [Re: RasJeph]
    #573036 - 07/18/11 05:56 PM (12 years, 8 months ago)

5-HTP: The Serotonin Connection

5-HTP is short for 5-hydroxy-tryptophan.  Unlike tryptophan, 5-HTP is not fermented or manufactured through chemical synthesis.  It is a natural extract from the seeds of the Griffonia plant.

Some physicians are using 5-HTP for Parkinson's disease, myclonus, anxiety, despression, appetite control, Alzheimer's disease, sleep disorders, autism, addictions, aggression, aging problems, dementia, and various other health problems.  It is considered experimental and classed as an investigational new drug.

Though only 1% to 2% of all serotonin in our bodies is found in the brain, it plays an important role in mediating our behavior and moods.

Serotonin cannot cross the blood-brain barrier, which means that it cannot leave the blood stream and pass into the brain tissue, as oxygen and other nutrients do.

Tryptophan, which does cross the blood-brain barrier, is actively transported into the brain where it is hydroxylated by the action of tryptophan hydroxylase at the 5 position, yielding the isolated intermediate (5-HTP).  Then the 5-HTP is rapidly decarboxylated by an amino acid decarboxylase to yield serotonin (5-HT).  These are instantaneous chemical reactions.

Serotonin, or 5-HT, affects thebrain in two different ways.  First, it has a hormonal effect.  The molecules diffuse outward and communicate with other cells, somehow influencing their functioning in a manner we do not completely understand.  The second effect, which is better understood, is through the normal action of neurotransmitters.

Although 5-HTP is a safe alternative to serotonin-enhancing drugs, several other compounds that increase serotonin have received some very bad press.  The first of these was tryptophan, the amino acid precursor to 5-HTP.  A bad batch of tryptophan, which contained a contaminant, was released by a single Japanese producer.  This contaminant caused breaked of a terrible disorder called eosinophilia myalgia syndrome (EMS).  As a result, the FDA banned the sale of all tryptophan in the American health food market.

Certain drugs taht seem to be effective in treating depression are called SSRIs, which stand for selective serotonin reuptake inhibitors.  As the name states, they inhibit the reuptake of serotonin and thereby increase its levels in the brain.  This category includes such drugs as Prozac, Paxil, Luvox, and Zoloft.

One interesting aspect of serotonin is its structural similarity to a number of hallucinogenic drugs, such as LSD.  These hallucinogens seem to partially inhibit the firing of serotonin neurons by competing with serotonin at the level of 5-HT receptors--fooling them because they possess a similar chemical structure.

Tryptophan levels in food:

Code:
Food                   --amount--     --Content(grams)--

Avocado............: 1 : .40
Cheese.............: 1 ounce : .09
Chicken............: 1 pound : .28
Chocolate..........: 1 pound : .11
Cottage Cheese.....: 1 cup : .40
Duck...............: 1 cup : .40
Egg................: 1 : .10
Granola............: 1 cup : .20
Luncheon Meat......: 1 pound : .50
Oatmeal............: 1 cup : .20
Pork...............: 1 pound : 1.00
Ricotta............: 1 cup : --
Sausage meat.......: 1 poound : .30
Turkey.............: 1 pound : .37
Wheat germ.........: 1 cup : .40
Whole milk.........: 1 cup : .11
Wild game..........: 1 pound : 1.15
Yogurt.............: 1 cup : .05


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