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Offlinespacemonkey69
Trusted Vaporizer

Registered: 12/22/08
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Drug Diagram.
    #322171 - 11/27/09 09:46 AM (7 years, 8 days ago)

And look who is at the pinnacle :awesome:



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[quote]
“You see this glass bong?” asks Achaan Chaa, the Thai meditation master. “For me this glass is already broken. I enjoy it; I smoke out of it. It holds my water admirably, sometimes even reflecting the sun in beautiful patterns. If I should tap it, it has a lovely ring to it. But when I put this glass bong on the shelf and the wind knocks it over or my elbow brushes it off the table and it falls to the ground and shatters, I say, ‘Of course.’ When I understand that the glass is already broken, every moment with it is precious.”[/quote]


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Offline81renaissance
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Re: Drug Diagram. [Re: spacemonkey69]
    #322174 - 11/27/09 10:06 AM (7 years, 8 days ago)

Ok that's just fuckin' cool.

There need to be more people researching this herb that has SO MANY properties, AND that binds to receptors in the brain whose only function is to process those chemicals.


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"So it goes."
-Kurt Vonnegut


BlueBerry_Swisher said:I want French fries. No, I want a penis French. Thank you. I'm so excited. I can not contain myself. Now I eat chocolate. It is so good. I'm trying to rub it all over myself. And then lick. Now I need a hot shower. The end.


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Offlinespacemonkey69
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Registered: 12/22/08
Posts: 1,018
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Re: Drug Diagram. [Re: 81renaissance]
    #322177 - 11/27/09 10:08 AM (7 years, 8 days ago)

Quote:

81renaissance said:
Ok that's just fuckin' cool.

There need to be more people researching this herb that has SO MANY properties, AND that binds to receptors in the brain whose only function is to process those chemicals.




QFT


--------------------
[quote]
“You see this glass bong?” asks Achaan Chaa, the Thai meditation master. “For me this glass is already broken. I enjoy it; I smoke out of it. It holds my water admirably, sometimes even reflecting the sun in beautiful patterns. If I should tap it, it has a lovely ring to it. But when I put this glass bong on the shelf and the wind knocks it over or my elbow brushes it off the table and it falls to the ground and shatters, I say, ‘Of course.’ When I understand that the glass is already broken, every moment with it is precious.”[/quote]


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Offlinespacemonkey69
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Registered: 12/22/08
Posts: 1,018
Loc: Flag
Last seen: 3 years, 7 months
Re: Drug Diagram. [Re: spacemonkey69]
    #322182 - 11/27/09 10:41 AM (7 years, 8 days ago)

Drugs are like pillows. They are there to cushion the blows of adversity in life. Something to fall in when you land on your face.  :thumbup:


--------------------
[quote]
“You see this glass bong?” asks Achaan Chaa, the Thai meditation master. “For me this glass is already broken. I enjoy it; I smoke out of it. It holds my water admirably, sometimes even reflecting the sun in beautiful patterns. If I should tap it, it has a lovely ring to it. But when I put this glass bong on the shelf and the wind knocks it over or my elbow brushes it off the table and it falls to the ground and shatters, I say, ‘Of course.’ When I understand that the glass is already broken, every moment with it is precious.”[/quote]


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InvisibleDr. SiekadellykM
Question Everything!
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Re: Drug Diagram. [Re: spacemonkey69]
    #322191 - 11/27/09 11:05 AM (7 years, 8 days ago)

yeah


then sometimes their like bricks that bitchslap you like stone gods


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The Kratom Report...


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Offlineb0b gnarley
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Re: Drug Diagram. [Re: 81renaissance]
    #322401 - 11/27/09 08:16 PM (7 years, 8 days ago)

Quote:

81renaissance said:
AND that binds to receptors in the brain whose only function is to process those chemicals.



thats not technically proven yet..


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Offlineneopet nub

Registered: 02/15/09
Posts: 20
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Re: Drug Diagram. [Re: b0b gnarley]
    #322943 - 11/29/09 01:27 PM (7 years, 6 days ago)

That is a great diagram! I always love looking at this then researching drugs and related drugs from it


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Offlinemeatcakeman
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Re: Drug Diagram. [Re: b0b gnarley]
    #323436 - 11/30/09 04:35 AM (7 years, 5 days ago)

Quote:

b0b gnarley said:
Quote:

81renaissance said:
AND that binds to receptors in the brain whose only function is to process those chemicals.



thats not technically proven yet..





What do you mean?


--------------------
sǝıqɐq ɹɐʇ


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Offlineb0b gnarley
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Re: Drug Diagram. [Re: meatcakeman]
    #323493 - 11/30/09 11:21 AM (7 years, 5 days ago)

Quote:

meatcakeman said:
Quote:

b0b gnarley said:
Quote:

81renaissance said:
AND that binds to receptors in the brain whose only function is to process those chemicals.



thats not technically proven yet..





What do you mean?



we should not be so rash to claim that cannabinoid receptors only bind to tetrahydrocannabinol's precurser cannabidiol:tomatoface:


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Offlinemeatcakeman
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Re: Drug Diagram. [Re: b0b gnarley]
    #323785 - 11/30/09 06:44 PM (7 years, 5 days ago)

Quote:

b0b gnarley said:
Quote:

meatcakeman said:
Quote:

b0b gnarley said:
Quote:

81renaissance said:
AND that binds to receptors in the brain whose only function is to process those chemicals.



thats not technically proven yet..





What do you mean?



we should not be so rash to claim that cannabinoid receptors only bind to tetrahydrocannabinol's precurser cannabidiol:tomatoface:





They don't.

Cannabinoid receptors are highly receptive to other cannabinoids as well, such as JWH compounds. Plus, our body makes a plethora of endocannabinoids that bind perfectly to our cannabinoid receptors, such as anandamide. CB1 and CB2 hold a lot of weight, neurologically speaking and in terms with anandamide. Anandamide, itself, regulates our ability to strategically and subconsciously remember and forget things. That is highly important for such neurological animals like us when memory is such a precious commodity; it's not like we need to remember every car we drove by on the freeway.


--------------------
sǝıqɐq ɹɐʇ


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InvisibleHarry_Ba11sachM
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Re: Drug Diagram. [Re: meatcakeman]
    #323849 - 11/30/09 07:43 PM (7 years, 5 days ago)

very interesting I didn't know that.

I suppose that increased activation of the receptors caused by trophic ingestion of cannabis could lead to more efficient functioning of anandamide in the brain, and theoretically explain why I saw such an enormous increase in my GPA when I started smoking weed


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Offlinemeatcakeman
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Re: Drug Diagram. [Re: Harry_Ba11sach]
    #323858 - 11/30/09 07:50 PM (7 years, 5 days ago)

Well, theoretically, other cannabinoids could substitute for anandamide as long as they can bind to the receptors. But, other cannabinoids come with their own array of unique effects, so you never really know how your body will react to it. Anandamide, itself, is not triggered by the ingestion of cannabis because it is made within us. Thus, it's flow is regulated by our biological rhythmic clock.

Right now, research on cannabinoids is minimal. So, we don't truly know how ingesting cannabinoids would affect the endocannabinoids within us.


--------------------
sǝıqɐq ɹɐʇ


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InvisibleHarry_Ba11sachM
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Re: Drug Diagram. [Re: meatcakeman]
    #323878 - 11/30/09 07:59 PM (7 years, 5 days ago)

right, the production levels wouldn't increase, but I'm saying that an increase in receptors commonly associated with tolerance could lead to a higher percentage of anandamide activating the receptors due to higher availability.

I'm just guessing tbh, most likely anandamide is produced in such low quantities that receptor saturation is a moot-point


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Offlinemeatcakeman
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Re: Drug Diagram. [Re: Harry_Ba11sach]
    #323892 - 11/30/09 08:08 PM (7 years, 5 days ago)

Quote:

Harry_Ba11sach said:
right, the production levels wouldn't increase, but I'm saying that an increase in receptors commonly associated with tolerance could lead to a higher percentage of anandamide activating the receptors due to higher availability.

I'm just guessing tbh, most likely anandamide is produced in such low quantities that receptor saturation is a moot-point





Hm. I'm not sure, but I don't think so.

Anandamide production doesn't really correlate to our cannabinoid receptors.

Anyways, we should all be careful with our cannabinoid receptors. Without CB1, intestinal tumors would run rapid.

God dammit, I love my major.


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sǝıqɐq ɹɐʇ


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