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Rust Fuckin' Cohle
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Registered: 03/20/10
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Spicy Food and Xanax
    #429961 - 06/08/10 05:01 PM (8 years, 16 days ago)

If these two things can't go together I will be sad.


β-endorphin is released into blood from the pituitary gland and into the spinal cord and brain from hypothalamic neurons. The β-endorphin that is released into the blood cannot enter the brain in large quantities because of the blood-brain barrier so the physiological importance of the β-endorphin that can be measured in the blood is far from clear. β-endorphin is a cleavage product of pro-opiomelanocortin (POMC) which is also the precursor hormone for adrenocorticotrophic hormone (ACTH). The behavioural effects of β-endorphin are exerted by its actions in the brain and spinal cord, and probably the hypothalamic neurons are the major source of β-endorphin at these sites. In situations where the level of ACTH is increased (e.g. Cushing’s Syndrome), the level of endorphins also increases slightly.

β-endorphin has the highest affinity for the μ1 opioid receptor, slightly lower affinity for the μ2 and δ opioid receptors and low affinity for the κ1 opioid receptors. μ opioid receptors are the main receptor through which morphine acts. Classically, μ opioid receptors are presynaptic, and inhibit neurotransmitter release; through this mechanism, they inhibit the release of the inhibitory neurotransmitter GABA, and disinhibit the dopamine pathways, causing more dopamine to be released. By hijacking this process, exogenous opioids cause inappropriate dopamine release, and lead to aberrant synaptic plasticity, which causes addiction. Opioid receptors have many other and more important roles in the brain and periphery however, modulating pain, cardiac, gastric and vascular function as well as possibly panic and satiation, and receptors are often found at postsynaptic locations as well as presynaptically.

What does this mean?
If I eat spicy food will it make xanax not work as well?

420th Post

Edited by FRACTALife (06/08/10 09:12 PM)

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Science Is Subculture
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Registered: 05/03/08
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Re: Spicy Food and Xanax [Re: FRACTALife]
    #429983 - 06/08/10 06:16 PM (8 years, 16 days ago)

I dunno man every time I get barred out I usually buy like 5 89c burritos and cover them in fire sauce, and then I just feel barred out and satisfied.... and sweaty

Glass By: US Tubes, ZOB, Roor.de, Sheldon Black, Jerome Baker, Medicali, Kennaroo, Sand, Alex K, Local and Unknown Artists

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Grease Wizard

Registered: 04/21/08
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Re: Spicy Food and Xanax [Re: FRACTALife]
    #429984 - 06/08/10 06:22 PM (8 years, 16 days ago)

It just means that you will not remember taking a spicy shit the next morning.

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CNC Machinist/Greenthumb
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Registered: 06/01/08
Posts: 9,953
Loc: North Star Flag
Re: Spicy Food and Xanax [Re: Tangerines]
    #429987 - 06/08/10 06:41 PM (8 years, 16 days ago)


Tangerines said:
It just means that you will not remember taking a spicy shit the next morning.


Don't criticize what you can't understand

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Lord of the Flies

Registered: 05/06/08
Posts: 9,372
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Re: Spicy Food and Xanax [Re: Tangerines]
    #429988 - 06/08/10 06:47 PM (8 years, 16 days ago)


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